
Kaohsiung Medical University
Kaohsiung Medical UniversityKaohsiung Medical University is a leading medical school in southern Taiwan and the Asia-Pacific region, with over seventy years of history in medical excellence. The strength of KMU lies in its outstanding students, as we recruit the best students from across the country every year. The university is not only a training institution for healthcare professionals but also an exceptional center for nurturing the most outstanding medical talent and leaders, with the goal of advancing societal progress.
Precision Drug Recommendation for Second-Generation Hormonal Therapy in Prostate Cancer
Solution Description
Our team has built predictive models based on whole transcriptome data from patients with advanced metastatic prostate cancer, focusing on two different mechanisms of action: androgen receptor antagonists and androgen synthesis inhibitors. These two types of drugs essentially offer only one chance of selection, as resistance to one renders the other ineffective. Using weighted gene correlation network analysis, we identified several gene modules correlated to specific drug responses. Then, we combined several machine-learning algorithms and constructed classification models for different drug mechanisms. Our goal is to use detection services to determine the most effective drug for patients before administration.
Download
Solutions









